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e-Book p53 (Molecular Biology Intelligence Unit) epub download

e-Book p53 (Molecular Biology Intelligence Unit) epub download

Author: Ayeda Ayed,Theodore Hupp
ISBN: 1441982302
Pages: 200 pages
Publisher: Springer; 2011 edition (December 16, 2010)
Language: English
Category: Medicine & Health Sciences
Size ePUB: 1384 kb
Size Fb2: 1389 kb
Size DJVU: 1689 kb
Rating: 4.2
Votes: 945
Format: mbr lrf mbr txt
Subcategory: Other

e-Book p53 (Molecular Biology Intelligence Unit) epub download

by Ayeda Ayed,Theodore Hupp

p53 (Molecular Biology Intelligence Unit). p53 (Molecular Biology Intelligence Unit). Ayeda Ayed, Theodore Hupp.

p53 (Molecular Biology Intelligence Unit). Download (pdf, . 7 Mb) Donate Read. Epub FB2 mobi txt RTF. Converted file can differ from the original. If possible, download the file in its original format.

AYEDA AYED is on leave from the Ontario Cancer Institute at the University of Toronto where she worked as a Postdoctoral Fellow . Molecular Biology Intelligence Unit.

AYEDA AYED is on leave from the Ontario Cancer Institute at the University of Toronto where she worked as a Postdoctoral Fellow and Associate Scientist on structural aspects of p53 using nuclear Magnetic Resonance Spectroscopy. She obtained her PhD in Chemistry at the University of Manitoba in Winnipeg and currently resides in Toronto, Canada.

Authors: Hupp, Theodore. TP53 Mutations in Human Cancers: Selection versus Mutagenesis - Lessons on p53 from Mouse Models - TP63, TP73: The Guardian’s Elder Brothers - The Regulation of p53 Protein Function by Phosphorylation - The p53-Mdm2 Loop: A Critical Juncture of Stress Response - Cooperation between MDM2 and MDMX in.

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Titles in this series will increasingly reflect issues peculiar to the post-genomic era. Recently published: . Dhar, M. Tomita (Ed. E‑Cell System. Basic Concepts and Applications, Vol. 118. A. Ayed, T. Hupp (Ed. p53. Vol. 1. N. Segev (E.

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Our understanding of human cancer in the past 40 years has been driven by linking innovative concepts and cutting edge technologies to key problems identified by clinical research. Some of the successes in cancer genetics identified from clinical work have been the identification of specific gene deletions in human chromosomes, the use of PCR-based cloning methodologies to identify and clone human cancer genes, the validation of the human cancer genes using transgenetic technologies in the mouse, and the ability to sequence whole genomes that has recently allowed a collation of all somatic and germline mutations in a human genome. In the same generation, entirely different disciplines involved in basic life science research have used model organisms like yeast, flies, worms, and cancer causing animal viruses as tools to develop windows to see into the machinery of the cell life cycle. The discoveries of pro-apoptotic genes, oncogenes, and covalent control mechanisms like phosphorylation and ubiquitination using the tools of science and technology have all been awarded Nobel prizes for their contribution to our understanding of how cells work. The discovery of p53 using the tumor causing animal virus SV40 falls into this pioneering period of biological and medical research.